Volume 1, Issue 2, December 2017, Page: 13-19
CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica
Md. Mamun-Or-Rashid, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Muhammad Ashiqul Islam, Department of Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Taniya Idris, Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Md. Shah Amran, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Received: Jun. 16, 2017;       Accepted: Jul. 5, 2017;       Published: Aug. 16, 2017
DOI: 10.11648/j.pst.20170102.11      View  1311      Downloads  64
Abstract
According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.
Keywords
Acacia Nilotica, CNS-Antidepressant Activity, Stem Bark and Methanolic Extract
To cite this article
Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran, CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica, Pharmaceutical Science and Technology. Vol. 1, No. 2, 2017, pp. 13-19. doi: 10.11648/j.pst.20170102.11
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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