Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa

Charles Nii Kwade Ofei-Palm; Naa Naamuah Tagoe; Dong Jatoe; Angela Agyare; Freda Suubam; Daniel Ankrah

doi:doi:10.11648/j.pst.20210502.13

| Peer-Reviewed

Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa

Charles Nii Kwade Ofei-Palm, Naa Naamuah Tagoe, Dong Jatoe, Angela Agyare, Freda Suubam, Daniel Ankrah

Published in Pharmaceutical Science and Technology (Volume 5, Issue 2)

Received: 27 August 2021 Accepted: 13 September 2021 Published: 26 September 2021

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

The World Health Organization (WHO) addressed drug utilization as the marketing, distribution, prescription and use of drugs in a society, considering its consequences, either medical, social, (and) or economic. The increasing importance of drug utilization studies as a valuable investigative resource in pharmacoepidemiology has bridged it with other health related areas, such as public health. Surveillance of drug use by the doctors within the institution as well as in the community is assuming an increasingly key role in therapeutics. This was a cross-sectional study of prescription pattern and drug utilization trends at the Lions International Eye Centre (LIEC) of the Korle Bu Teaching Hospital and adherence to the standard prescription form at the Eye Centre. Prescriptions that were presented to the LIEC pharmacy unit within the period from October 2015 to March 2016 were captured and reviewed. The total number of drugs in the 588 prescriptions was 1265. The average number of drugs per prescription was 2.1. Drug dosage, route of administration, frequency, and duration of treatment record were mentioned in 95.01% (1202/1265), 97% (1227/1265), 98.46% (1240/1265) 96.05% (1215/1265) of the prescriptions respectively. Anti-glaucoma medicines were the most prescribed 21.8% (276/1265), Prescribing by generic name slightly dominated with 51.1% (645/1265) of the total number of drugs prescribed. Use of Ophthalmic antibiotics alone and the use of ophthalmic antibiotics in combination with other medicines were 13.5% (171/1265) and 11.9% (142/1265) respectively.: The findings of this study revealed that the drug utilization pattern was not in line with the recommended standard values of WHO prescribing indicators even though the level of compliance to the requirements on the standard prescription form of the hospital for drug prescribers was remarkably high. The availability of key medicines should be improved whilst generic prescribing from EDL should also be encouraged.

Published in	Pharmaceutical Science and Technology (Volume 5, Issue 2)
DOI	10.11648/j.pst.20210502.13
Page(s)	44-49
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Drug Utilization, Ophthalmology, Prescription, Korle Bu, West Africa

References

[1]	World Health Organization (WHO) and International Network for Rational Use of Drugs (1993). How to Investigate Drug Use in Health Facilities: Selected Drug Use indicators, WHO/DAP/93.1, WHO, Geneva, Switzerland.
[2]	World Health Organization (WHO) International Working Group for Drug Statistics Methodology, WHO Collaborating Centre for Drug Statistics Methodology, WHO Collaborating Centre for Drug Utilization Research and Clinical Pharmacological Services (2003). Introduction to Drug Utilization Research, WHO, Oslo, Norway.
[3]	World Health Organization, Introduction to Drug Utilization Research, WHO, Oslo, Norway, 2003. Available at: http://apps.who.int/medicinedocs/ en/d/Js4876e/. Accessed on 3 November 2020.
[4]	Lunde PK, Baksaas I (1988). Epidemiology of drug utilization basic concepts and methodology. Acta Med Scand Suppl; 721: 7-11.
[5]	Strom BL. Pharmacoepidemiology (2005). Fourth ed: John Wiley & Sons, Ltd.
[6]	Costa, J., de Oliveira, E. I., Rosa, M. M., Ferreira, J. J., Sampaio, C., & Carneiro, A. V. (2001). Cardiac effects of acute poisoning with tricyclic antidepressants: systematic review of the literature -- Part IV]. Portuguese journal of cardiology: an official journal of the Portuguese Society of Cardiology, 20 (10), 1021–1030.
[7]	GAMA, Helena (2008). Drug Utilization Studies. Arq Med., 22 (2-3): 69-74.
[8]	Shaheen Saeeda, Parvez Saeedb, Varun Sharmaa (2012). Current scenario of rational usage of various drugs in indoor patients. Int J Basic Clin Pharmacol, Aug; 1 (1): 27-31.
[9]	Benet LZ (1996). Principles of prescription order writing and patients compliance instructions. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG editors. Goodman and Gilman’s. The pharmacological Basis of Therapeutics. 9th Ed. New York; mcgraw Hill 1617-706.
[10]	WHO (2011). 17th WHO Model list of essential medicines: WHO Technical Report Series, No. 920.
[11]	World Health Organization. (‎2012)‎. The pursuit of responsible use of medicines: sharing and learning from country experiences. World Health Organization. https://apps.who.int/iris/handle/10665/75828. accessed July 17, 2020.
[12]	De Vries, T. P. G. M, Henning, R. H, Hogerzeil, Hans V, Fresle, D. A, WHO Action Programme on Essential Drugs. et al. (‎1994)‎. Guide to good prescribing: a practical manual / authors: T. P. G. M. de Vries. [‎et al.]‎; with contributions from F. M. Haaijer-Ruskamp and R. M. van Gilst. World Health Organization. https://apps.who.int/iris/handle/10665/59001 Accessed July 17, 2020.
[13]	Singh S, Ansari KU, Kastury N, Pandey RC (1997). An audit of prescription for rational use of antibiotics. Indian J Pharmacol; 18: 77-81.
[14]	Ansari KU, Singh S, Pandey RC (1998). Evaluation of prescribing patterns of doctors for rational drug therapy. Indian J Pharmacol, 30: 43-6.
[15]	Ghana Health Service. Ghana health service-ethics review committee: standard operating procedures; 2015. Available from: https://www.ghanahealthservice.org/downloads/Standard_Operating_Procedures.pdf. Accessed August 12, 2020.
[16]	Singh J, iswas NR, Jain JS, and Das GK (1998), prescribing trends in ophthalmology. The Indian Journal of Clinical Pharmacology and Therapeutics, 18: 79-82.
[17]	Maniyar Y, Bhixavatimath P, and Akkone V (2011.), A drug utilization study in the ophthalmology department of a medical college, Karnataka, India,” Journal of Clinical and Diagnostic Research, 5: 82–84.
[18]	Jain VP, hrivastava B, and Agarwal M, 2011) Drug utilization pattern of drugs used along ophthalmic antiallergics formulations used in patients diagnosed with seasonal and perennial allergic conjunctivitis. Asian Journal of Pharmaceutical Sciences and Research, 1: 15–20.
[19]	Nies AS (1990.). Principles of therapeutics. In: Gilman AG, Rall TW, Nies AS, editors. The Pharmacological Basis of Therapeutics Eighth Edition. New York: Pergamon Press; 62–83.
[20]	Kumari P, Gari K, and Pathak, A. (2019). A study of the current prescribing and drug utilization pattern in Ophthalmology Department of a tertiary care teaching hospital. International Journal of Basic & Clinical Pharmacology, 8: 497-501. doi: http://dx.doi.org/10.18203/2319-2003.ijbcp20190654J.
[21]	Biswas NR, Jindal S, Siddiquei MM, Maini R (2001). Patterns of prescription and drug use in ophthalmology in a tertiary hospital in Delhi. Br J Clin Pharmacol, 51: 267-9.
[22]	Nehru M, Kohli K, Kapoor P, Sadhotra P, Chopra V, and Sharma R 2005). Drug utilization study in outpatient ophthalmology department of Government Medical College Jammu,” JK Science, 7: 149–151.
[23]	WHO. (2011) WORLD MEDICINES SITUATION. http://apps.who.int/medicinedocs/en/d/Js6160e/ accessed February 27, 2020.
[24]	Jadhav, P. R., Moghe, V. V., & Deshmukh, Y. A. (2013). Drug utilization study in ophthalmology outpatients at a tertiary care teaching hospital. ISRN pharmacology, 2013, 768792. https://doi.org/10.1155/2013/768792.
[25]	Ofei-Palm CNK, Tagoe NN, Jatoe D, Agyare A, Ankrah D. Cost Analysis and Rational Use of Anti-Glaucoma Therapy in a Tertiary Hospital in Ghana. Clinicoecon Outcomes Res. 2021; 13: 619-627. Published 2021 Jul 2. doi: 10.2147/CEOR.S311058.
[26]	Jain AK, Jain S, Sharma V, Pandey DJ, Shukla A (2018). Drug Utilization Study In Ophthalmology Outpatient Department In A Government Tertiary Care Hospital In Maharashtra. Asian Journal of Pharmaceutical and Clinical Research, 11 (7), 267–270. https://doi.org/10.22159/ajpcr.2018.v11i7.25995.
[27]	Janaki Devi C. H, Seethalakshmi S, Devaraj S. (2020). Drug utilization study in ophthalmology out patients in a tertiary care teaching hospital. International Journal of Basic & Clinical Pharmacology, 9 (11), 1721-1724. doi: http://dx.doi.org/10.18203/2319-2003.ijbcp20204501.
[28]	World Health Organization. Action Programme on Essential Drugs and Vaccines. (‎1992)‎. Essential drugs: action for equity. World Health Organization. https://apps.who.int/iris/handle/10665/58957 Accessed July 18 2020.
[29]	World Health Organization. Action Programme on Essential Drugs and Vaccines. (‎1993)‎. How to investigate drug use in health facilities: selected drug use indicators. World Health Organization. https://apps.who.int/iris/handle/10665/60519 Accessed July 18 2020.

Cite This Article

Plain Text BibTeX RIS

APA Style

Charles Nii Kwade Ofei-Palm, Naa Naamuah Tagoe, Dong Jatoe, Angela Agyare, Freda Suubam, et al. (2021). Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa. Pharmaceutical Science and Technology, 5(2), 44-49. https://doi.org/10.11648/j.pst.20210502.13

Copy | Download

ACS Style

Charles Nii Kwade Ofei-Palm; Naa Naamuah Tagoe; Dong Jatoe; Angela Agyare; Freda Suubam, et al. Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa. Pharm. Sci. Technol. 2021, 5(2), 44-49. doi: 10.11648/j.pst.20210502.13

Copy | Download

AMA Style

Charles Nii Kwade Ofei-Palm, Naa Naamuah Tagoe, Dong Jatoe, Angela Agyare, Freda Suubam, et al. Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa. Pharm Sci Technol. 2021;5(2):44-49. doi: 10.11648/j.pst.20210502.13

Copy | Download

@article{10.11648/j.pst.20210502.13,
  author = {Charles Nii Kwade Ofei-Palm and Naa Naamuah Tagoe and Dong Jatoe and Angela Agyare and Freda Suubam and Daniel Ankrah},
  title = {Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa},
  journal = {Pharmaceutical Science and Technology},
  volume = {5},
  number = {2},
  pages = {44-49},
  doi = {10.11648/j.pst.20210502.13},
  url = {https://doi.org/10.11648/j.pst.20210502.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.pst.20210502.13},
  abstract = {The World Health Organization (WHO) addressed drug utilization as the marketing, distribution, prescription and use of drugs in a society, considering its consequences, either medical, social, (and) or economic. The increasing importance of drug utilization studies as a valuable investigative resource in pharmacoepidemiology has bridged it with other health related areas, such as public health. Surveillance of drug use by the doctors within the institution as well as in the community is assuming an increasingly key role in therapeutics. This was a cross-sectional study of prescription pattern and drug utilization trends at the Lions International Eye Centre (LIEC) of the Korle Bu Teaching Hospital and adherence to the standard prescription form at the Eye Centre. Prescriptions that were presented to the LIEC pharmacy unit within the period from October 2015 to March 2016 were captured and reviewed. The total number of drugs in the 588 prescriptions was 1265. The average number of drugs per prescription was 2.1. Drug dosage, route of administration, frequency, and duration of treatment record were mentioned in 95.01% (1202/1265), 97% (1227/1265), 98.46% (1240/1265) 96.05% (1215/1265) of the prescriptions respectively. Anti-glaucoma medicines were the most prescribed 21.8% (276/1265), Prescribing by generic name slightly dominated with 51.1% (645/1265) of the total number of drugs prescribed. Use of Ophthalmic antibiotics alone and the use of ophthalmic antibiotics in combination with other medicines were 13.5% (171/1265) and 11.9% (142/1265) respectively.: The findings of this study revealed that the drug utilization pattern was not in line with the recommended standard values of WHO prescribing indicators even though the level of compliance to the requirements on the standard prescription form of the hospital for drug prescribers was remarkably high. The availability of key medicines should be improved whilst generic prescribing from EDL should also be encouraged.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa
AU  - Charles Nii Kwade Ofei-Palm
AU  - Naa Naamuah Tagoe
AU  - Dong Jatoe
AU  - Angela Agyare
AU  - Freda Suubam
AU  - Daniel Ankrah
Y1  - 2021/09/26
PY  - 2021
N1  - https://doi.org/10.11648/j.pst.20210502.13
DO  - 10.11648/j.pst.20210502.13
T2  - Pharmaceutical Science and Technology
JF  - Pharmaceutical Science and Technology
JO  - Pharmaceutical Science and Technology
SP  - 44
EP  - 49
PB  - Science Publishing Group
SN  - 2640-4540
UR  - https://doi.org/10.11648/j.pst.20210502.13
AB  - The World Health Organization (WHO) addressed drug utilization as the marketing, distribution, prescription and use of drugs in a society, considering its consequences, either medical, social, (and) or economic. The increasing importance of drug utilization studies as a valuable investigative resource in pharmacoepidemiology has bridged it with other health related areas, such as public health. Surveillance of drug use by the doctors within the institution as well as in the community is assuming an increasingly key role in therapeutics. This was a cross-sectional study of prescription pattern and drug utilization trends at the Lions International Eye Centre (LIEC) of the Korle Bu Teaching Hospital and adherence to the standard prescription form at the Eye Centre. Prescriptions that were presented to the LIEC pharmacy unit within the period from October 2015 to March 2016 were captured and reviewed. The total number of drugs in the 588 prescriptions was 1265. The average number of drugs per prescription was 2.1. Drug dosage, route of administration, frequency, and duration of treatment record were mentioned in 95.01% (1202/1265), 97% (1227/1265), 98.46% (1240/1265) 96.05% (1215/1265) of the prescriptions respectively. Anti-glaucoma medicines were the most prescribed 21.8% (276/1265), Prescribing by generic name slightly dominated with 51.1% (645/1265) of the total number of drugs prescribed. Use of Ophthalmic antibiotics alone and the use of ophthalmic antibiotics in combination with other medicines were 13.5% (171/1265) and 11.9% (142/1265) respectively.: The findings of this study revealed that the drug utilization pattern was not in line with the recommended standard values of WHO prescribing indicators even though the level of compliance to the requirements on the standard prescription form of the hospital for drug prescribers was remarkably high. The availability of key medicines should be improved whilst generic prescribing from EDL should also be encouraged.
VL  - 5
IS  - 2
ER  -

Copy | Download

Author Information

Charles Nii Kwade Ofei-Palm

Lions International Eye Centre (LIEC), Pharmacy Unit, Korle Bu Teaching Hospital, Accra, Ghana
Naa Naamuah Tagoe

Lions International Eye Centre (LIEC), Korle Bu Teaching Hospital, Accra, Ghana
Dong Jatoe

Lions International Eye Centre (LIEC), Pharmacy Unit, Korle Bu Teaching Hospital, Accra, Ghana
Angela Agyare

Lions International Eye Centre (LIEC), Pharmacy Unit, Korle Bu Teaching Hospital, Accra, Ghana
Freda Suubam

Lions International Eye Centre (LIEC), Pharmacy Unit, Korle Bu Teaching Hospital, Accra, Ghana
Daniel Ankrah

Pharmacy Department, Korle Bu Teaching Hospital, Accra, Ghana

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Charles Nii Kwade Ofei-Palm, Naa Naamuah Tagoe, Dong Jatoe, Angela Agyare, Freda Suubam, et al. (2021). Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa. Pharmaceutical Science and Technology, 5(2), 44-49. https://doi.org/10.11648/j.pst.20210502.13

Copy | Download

ACS Style

Charles Nii Kwade Ofei-Palm; Naa Naamuah Tagoe; Dong Jatoe; Angela Agyare; Freda Suubam, et al. Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa. Pharm. Sci. Technol. 2021, 5(2), 44-49. doi: 10.11648/j.pst.20210502.13

Copy | Download

AMA Style

Charles Nii Kwade Ofei-Palm, Naa Naamuah Tagoe, Dong Jatoe, Angela Agyare, Freda Suubam, et al. Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa. Pharm Sci Technol. 2021;5(2):44-49. doi: 10.11648/j.pst.20210502.13

Copy | Download

@article{10.11648/j.pst.20210502.13,
  author = {Charles Nii Kwade Ofei-Palm and Naa Naamuah Tagoe and Dong Jatoe and Angela Agyare and Freda Suubam and Daniel Ankrah},
  title = {Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa},
  journal = {Pharmaceutical Science and Technology},
  volume = {5},
  number = {2},
  pages = {44-49},
  doi = {10.11648/j.pst.20210502.13},
  url = {https://doi.org/10.11648/j.pst.20210502.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.pst.20210502.13},
  abstract = {The World Health Organization (WHO) addressed drug utilization as the marketing, distribution, prescription and use of drugs in a society, considering its consequences, either medical, social, (and) or economic. The increasing importance of drug utilization studies as a valuable investigative resource in pharmacoepidemiology has bridged it with other health related areas, such as public health. Surveillance of drug use by the doctors within the institution as well as in the community is assuming an increasingly key role in therapeutics. This was a cross-sectional study of prescription pattern and drug utilization trends at the Lions International Eye Centre (LIEC) of the Korle Bu Teaching Hospital and adherence to the standard prescription form at the Eye Centre. Prescriptions that were presented to the LIEC pharmacy unit within the period from October 2015 to March 2016 were captured and reviewed. The total number of drugs in the 588 prescriptions was 1265. The average number of drugs per prescription was 2.1. Drug dosage, route of administration, frequency, and duration of treatment record were mentioned in 95.01% (1202/1265), 97% (1227/1265), 98.46% (1240/1265) 96.05% (1215/1265) of the prescriptions respectively. Anti-glaucoma medicines were the most prescribed 21.8% (276/1265), Prescribing by generic name slightly dominated with 51.1% (645/1265) of the total number of drugs prescribed. Use of Ophthalmic antibiotics alone and the use of ophthalmic antibiotics in combination with other medicines were 13.5% (171/1265) and 11.9% (142/1265) respectively.: The findings of this study revealed that the drug utilization pattern was not in line with the recommended standard values of WHO prescribing indicators even though the level of compliance to the requirements on the standard prescription form of the hospital for drug prescribers was remarkably high. The availability of key medicines should be improved whilst generic prescribing from EDL should also be encouraged.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Drug Utilization Study in Ophthalmology Outpatient Department of a Tertiary Care Hospital in West Africa
AU  - Charles Nii Kwade Ofei-Palm
AU  - Naa Naamuah Tagoe
AU  - Dong Jatoe
AU  - Angela Agyare
AU  - Freda Suubam
AU  - Daniel Ankrah
Y1  - 2021/09/26
PY  - 2021
N1  - https://doi.org/10.11648/j.pst.20210502.13
DO  - 10.11648/j.pst.20210502.13
T2  - Pharmaceutical Science and Technology
JF  - Pharmaceutical Science and Technology
JO  - Pharmaceutical Science and Technology
SP  - 44
EP  - 49
PB  - Science Publishing Group
SN  - 2640-4540
UR  - https://doi.org/10.11648/j.pst.20210502.13
AB  - The World Health Organization (WHO) addressed drug utilization as the marketing, distribution, prescription and use of drugs in a society, considering its consequences, either medical, social, (and) or economic. The increasing importance of drug utilization studies as a valuable investigative resource in pharmacoepidemiology has bridged it with other health related areas, such as public health. Surveillance of drug use by the doctors within the institution as well as in the community is assuming an increasingly key role in therapeutics. This was a cross-sectional study of prescription pattern and drug utilization trends at the Lions International Eye Centre (LIEC) of the Korle Bu Teaching Hospital and adherence to the standard prescription form at the Eye Centre. Prescriptions that were presented to the LIEC pharmacy unit within the period from October 2015 to March 2016 were captured and reviewed. The total number of drugs in the 588 prescriptions was 1265. The average number of drugs per prescription was 2.1. Drug dosage, route of administration, frequency, and duration of treatment record were mentioned in 95.01% (1202/1265), 97% (1227/1265), 98.46% (1240/1265) 96.05% (1215/1265) of the prescriptions respectively. Anti-glaucoma medicines were the most prescribed 21.8% (276/1265), Prescribing by generic name slightly dominated with 51.1% (645/1265) of the total number of drugs prescribed. Use of Ophthalmic antibiotics alone and the use of ophthalmic antibiotics in combination with other medicines were 13.5% (171/1265) and 11.9% (142/1265) respectively.: The findings of this study revealed that the drug utilization pattern was not in line with the recommended standard values of WHO prescribing indicators even though the level of compliance to the requirements on the standard prescription form of the hospital for drug prescribers was remarkably high. The availability of key medicines should be improved whilst generic prescribing from EDL should also be encouraged.
VL  - 5
IS  - 2
ER  -

Copy | Download