Background: Moisture content varies in capsules made from different materials. Gelatin capsules contain 13-16% moisture. HPMC (Hydroxypropyl methyl cellulose or Hypromellose) capsules may contain moisture 2- 8%. Usual HPMC capsules have inherently low moisture content which allows for the encapsulation of ingredients that are sensitive to moisture and are hygroscopic in nature. This has greatly broadened the scope of capsules in drug delivery. Moisture content of HPMC capsules can be reduced as low as 2%. HPMC capsules lower moisture content is better for moisture sensitive and hygroscopic products. Objective: Low moisture content of HPMC capsules help to improve stability of moisture sensitive active pharmaceutical and active nutraceutical active ingredients. This is illustrated with examples. Different properties of HPMC capsules helps targeted delivery. It offers some special advantages for nutraceutical products. It also helps to improve physical stability of capsules. Liquid filled hard capsules provide many options and are commonly used for nutraceutical products.
| Published in | Pharmaceutical Science and Technology (Volume 5, Issue 2) |
| DOI | 10.11648/j.pst.20210502.14 |
| Page(s) | 50-52 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
HPMC Capsules, Moisture Sensitive Products, Hygroscopic Products, Liquid-filled Hard Capsules
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APA Style
Milind Biyani. (2021). HPMC Capsules for Moisture Sensitive and Hygroscopic Products. Pharmaceutical Science and Technology, 5(2), 50-52. https://doi.org/10.11648/j.pst.20210502.14
ACS Style
Milind Biyani. HPMC Capsules for Moisture Sensitive and Hygroscopic Products. Pharm. Sci. Technol. 2021, 5(2), 50-52. doi: 10.11648/j.pst.20210502.14
AMA Style
Milind Biyani. HPMC Capsules for Moisture Sensitive and Hygroscopic Products. Pharm Sci Technol. 2021;5(2):50-52. doi: 10.11648/j.pst.20210502.14
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Download@article{10.11648/j.pst.20210502.14,
author = {Milind Biyani},
title = {HPMC Capsules for Moisture Sensitive and Hygroscopic Products},
journal = {Pharmaceutical Science and Technology},
volume = {5},
number = {2},
pages = {50-52},
doi = {10.11648/j.pst.20210502.14},
url = {https://doi.org/10.11648/j.pst.20210502.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.pst.20210502.14},
abstract = {Background: Moisture content varies in capsules made from different materials. Gelatin capsules contain 13-16% moisture. HPMC (Hydroxypropyl methyl cellulose or Hypromellose) capsules may contain moisture 2- 8%. Usual HPMC capsules have inherently low moisture content which allows for the encapsulation of ingredients that are sensitive to moisture and are hygroscopic in nature. This has greatly broadened the scope of capsules in drug delivery. Moisture content of HPMC capsules can be reduced as low as 2%. HPMC capsules lower moisture content is better for moisture sensitive and hygroscopic products. Objective: Low moisture content of HPMC capsules help to improve stability of moisture sensitive active pharmaceutical and active nutraceutical active ingredients. This is illustrated with examples. Different properties of HPMC capsules helps targeted delivery. It offers some special advantages for nutraceutical products. It also helps to improve physical stability of capsules. Liquid filled hard capsules provide many options and are commonly used for nutraceutical products.},
year = {2021}
}
TY - JOUR T1 - HPMC Capsules for Moisture Sensitive and Hygroscopic Products AU - Milind Biyani Y1 - 2021/09/30 PY - 2021 N1 - https://doi.org/10.11648/j.pst.20210502.14 DO - 10.11648/j.pst.20210502.14 T2 - Pharmaceutical Science and Technology JF - Pharmaceutical Science and Technology JO - Pharmaceutical Science and Technology SP - 50 EP - 52 PB - Science Publishing Group SN - 2640-4540 UR - https://doi.org/10.11648/j.pst.20210502.14 AB - Background: Moisture content varies in capsules made from different materials. Gelatin capsules contain 13-16% moisture. HPMC (Hydroxypropyl methyl cellulose or Hypromellose) capsules may contain moisture 2- 8%. Usual HPMC capsules have inherently low moisture content which allows for the encapsulation of ingredients that are sensitive to moisture and are hygroscopic in nature. This has greatly broadened the scope of capsules in drug delivery. Moisture content of HPMC capsules can be reduced as low as 2%. HPMC capsules lower moisture content is better for moisture sensitive and hygroscopic products. Objective: Low moisture content of HPMC capsules help to improve stability of moisture sensitive active pharmaceutical and active nutraceutical active ingredients. This is illustrated with examples. Different properties of HPMC capsules helps targeted delivery. It offers some special advantages for nutraceutical products. It also helps to improve physical stability of capsules. Liquid filled hard capsules provide many options and are commonly used for nutraceutical products. VL - 5 IS - 2 ER -
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